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2025 RBC Heritage one and done picks, sleepers, rankings: Top PGA Tour predictions, expert golf betting advice

The PGA Tour is set to make its annual trip to Harbour Town Golf Links for the 2025 RBC Heritage. Play gets underway in Hilton Head, S.C. on Thursday, April 17. As a signature event, the 2025 RBC Heritage purse is $20 million, with the winner taking home $3.6 million. World No. 1 Scottie Scheffler headlines the 2025 RBC Heritage field, and enters the event as the defending tournament champion and betting favorite. Scheffler is listed at +360 (risk $100 to win $360) in the 2025 RBC Heritage odds at . Other top contenders in the RBC Heritage field include Collin Morikawa (11-1), Xander Schauffele (11-1), Ludvig Åberg (12-1), Justin Thomas (16-1), Patrick Cantlay (18-1), and Shane Lowry (22-1).

As we head into the heart of the PGA Tour schedule, it is imperative to nail your 2025 RBC Heritage one and done picks. Should you use this event to target a favorite like Scheffler or Morikawa? Would it make sense to take a long shot like Min Woo Lee (55-1) or Justin Rose (70-1)? Before locking in your 2025 RBC Heritage one and done picks, you need to see what SportsLine DFS pro and PGA expert Mike McClure has to say. 

The One and Done format is growing in popularity. It has several noticeable similarities to NFL Survivor pools, with the main difference being entries are not eliminated with a bad week. Players pick one golfer per week and earn points based on their selected golfer’s prize money for that tournament. Golfers can only be used once per season, and the point format makes nailing majors and big money tournaments critical.

McClure is a DFS legend with over $2 million in career winnings, and he’s been red-hot on his PGA picks dating back to the PGA Tour restart in June of 2020. McClure uses his proprietary simulation model to analyze the field and crush his golf picks. In fact, the model is up more than $9,500 on its best bets since June 2020, nailing tournament after tournament.

This same model has also nailed a whopping 14 majors entering the weekend, including the 2025 Masters – its fourth Masters in a row – and last year’s PGA Championship and U.S. Open. Anyone who has followed it could have seen massive returns.

McClure has been nailing his One and Done picks for the last two years, correctly calling Nick Taylor’s epic win at the RBC Canadian Open, as well as Scottie Scheffler’s and Jon Rahm’s victories as the Masters. 

This season, McClure has been red-hot again. His top One and Done pick at the Genesis Invitational, Ludvig Aberg, outlasted the field for an outright win, taking home $3.6 million. He followed that up by listing eventual champion Rory McIlroy as his top OAD pick at the 2025 Masters.

Now, McClure has dialed in on the 2025 RBC Heritage golf tournament and just locked in his one and done picks and PGA predictions. They are a must-see for any player looking for an edge in their One and Done pool. You can only see McClure’s Houston Open one and done picks at SportsLine.

Top 2025 RBC Heritage One and Done picks

One of McClure’s top One and Done picks for the 2025 RBC Heritage is Jordan Spieth. The 31-year-old has 13 career PGA Tour victories and three major championships on his professional resume. In 2025, Spieth has four top-15 and two top-10 finishes, and he won this event in 2022.

Spieth has been streaky this season, but when he’s playing well, very few golfers in the world are on his level. Spieth enters this week ranked 32nd on the PGA Tour in total strokes gained (0.707), 46th in strokes gained tee-to-green (0.496), and 47th in strokes gained around the green (0.209). With his recent form (T14 at the Masters) and his status as one of the most accomplished players in the field, McClure is expecting Spieth to be in contention until the end this weekend. You can see who else to back at SportsLine.

How to make RBC Heritage 2025 One and Done picks

McClure is also targeting another golfer for his 2025 RBC Heritage one and done picks who was outstanding throughout the 2024 season and is a 45-1 longshot. This player has championship pedigree and has the ability to win any tournament he enters. You can find out who it is, and check out all of McClure’s RBC Heritage one and done picks at SportsLine.

Who wins the the RBC Heritage 2025, and which golfers should you target for your PGA one and done picks this week? Visit SportsLine now to get Mike McClure’s RBC Heritage 2025 one and done picks, all from the DFS pro who nailed Ludvig Aberg’s outright win at the Genesis Invitational and Rory McIlroy’s win at the Masters, and find out.





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