Thunder vs. Spurs prediction, odds, time: 2026 NBA picks for Wednesday, Feb. 4

The top two teams in the Western Conference will meet on Wednesday’s NBA schedule as the Oklahoma City Thunder visit the San Antonio Spurs. The Thunder (40-11) are 18-6 on the road and are coming off a 128-92 win over Orlando on Tuesday. The Spurs (33-16) are 17-6 at home and also defeated the Magic in their last contest by a 112-103 score on Sunday. Stephon Castle (adductor) and Dylan Harper (ankle) are both questionable for the Spurs. OKC has a lengthy injury list that includes top-three scorers Shai Gilgeous-Alexander (abdominal), Chet Holmgren (back) and Jalen Williams (hamstring) all ruled out. 

Tipoff is at 9:30 p.m. ET from Frost Bank Center in San Antonio. After OKC opened as a small favorite, the latest Spurs vs. Thunder odds now list San Antonio as the 9.5-point favorite, with the over/under at 220.5. Before making any Thunder vs. Spurs picks, check out the NBA predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model enters Week 16 of the 2025-26 NBA season on a sizzling 38-16 roll on top-rated NBA spread picks dating back to last season. Anyone following its NBA betting advice at sportsbooks and on betting apps could have seen huge returns.

Now, the model has simulated Spurs vs. Thunder 10,000 times and just revealed its coveted NBA picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several NBA odds and NBA betting lines for Thunder vs. Spurs: 

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How to make Thunder vs. Spurs picks

SportsLine’s model has simulated Spurs vs. Thunder 10,000 times and is going Over on the total (220.5 points). Four of the last five meetings between these teams in San Antonio have gone over, including each of the last two. Additionally, four of the last five road games for the Thunder, overall, have eclipsed the total. OKC’s Over record on the road this season is 14-10 which is the fifth-best over mark in the NBA.

The model is projecting 230 combined points as the Over hits 65% of the time.

It also says one side of the spread hits nearly 70% of the time. You can head to SportsLine to see the model’s NBA picks. 

So who wins Thunder vs. Spurs, and which side of the spread hits nearly 70% of the time? Visit SportsLine now to see which side of the Spurs vs. Thunder spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out.