
The 2025-26 college basketball schedule rolls along on Wednesday, Nov. 19, with 50 games involving Division I teams, including two ranked matchups. A top-five showdown has No. 3 UConn favored by 7.5 points versus the fourth-ranked Arizona Wildcats at 7 p.m. ET in the latest college basketball lines. Then, Illinois vs. Alabama has the eighth-ranked Illini as 3.5-point favorites over the No. 11 Crimson Tide, with Bama coming off a loss to Purdue. Other ranked teams to make Wednesday college basketball bets on include No. 7 Michigan vs. Middle Tennessee (+27.5) and No. 22 Auburn vs. Jackson State (+29.5).
Additional college basketball odds of note include Penn State vs. Harvard (+12.5), Villanova vs. La Salle (+12.5) and Marquette vs. Dayton (+5.5). After a couple of weeks of play, betting trends are starting to develop, which will only aid with finding the best picks to form a winning college basketball parlay. Before locking in any college basketball picks, you’ll want to see the college basketball predictions and betting advice from SportsLine’s proven computer model.
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The SportsLine Projection Model simulates every college basketball game 10,000 times and has returned over $2,000 in betting profit for $100 players on its top-rated college basketball picks over the past three-plus seasons. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen strong returns.
Now, the model has scoured the latest college basketball odds and locked in three confident college basketball picks. If you successfully parlay its college basketball betting picks, you’d be looking at a payout of nearly +1000. You can only see the model’s college basketball picks at SportsLine.
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Top college basketball picks for Wednesday, Nov. 19
After simulating every game 10,000 times, the model is backing UConn (-7.5) to cover versus Arizona at 7 p.m. ET. Dan Hurley has a veteran squad, with the top seven Huskies scorers being upperclassmen, including three of them being holdovers from the last UConn championship team. They are efficient on offense, ranking fifth in the nation in field goal percentage, and UConn owns the paint on the defensive end. Both Tarris Reed Jr. and Eric Reibe average at least one blocked shot a game, which should cause problems for an Arizona team which struggles from the perimeter.
Just 11 teams in Division I attempt fewer three-pointers than the Wildcats, as they rank 294th in the country in made three-pointers per game. They’re averaging just four made three-pointers per game versus teams from power conferences as only two Wildcats are projected to score in double-figures on Wednesday. That’s half as many as the Huskies are forecasted to have, as the simulations have UConn (-7.5) winning by double-digits.
SportsLine’s model projects the Huskies to cover in well over 60% of simulations. See which other college basketball parlay picks to make here, and bet this pick right here:
How to make college basketball predictions for Wednesday, Nov. 19
The model also has locked in two other picks, including an underdog of over 5 points that outright wins. You can only see the model’s college basketball parlay at SportsLine.
What are the model’s top college basketball parlay picks for Wednesday, and which best bets should you target for a chance at a payout of almost +1000. Visit SportsLine now to see college basketball best bets from a model that has returned over $2,000 in betting profit on its top-rated picks over the past three-plus seasons, and find out.

